High affinity choline transporter 1-like

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August undefined, 2024

Web103133831 - Gene ResultLOC103133831 high-affinity choline transporter 1-like [ (Amazon molly)] Gene provides a unified query environment for genes defined by … Web8 de mar. de 2006 · Interestingly, mutation of this dileucine-like motif attenuates internalization of CHT1 and increases choline uptake similarly to over-expression of either dynamin I-K44A or AP180-C, suggesting that this motif is responsible for most, if not all, of the clathrin-mediated internalization of the high-affinity choline transporter (Ribeiro et …

LOC103133831 high-affinity choline transporter 1-like [ (Amazon …

WebProtein target information for High affinity choline transporter 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. Web20 de set. de 2024 · Choline is a positively charged quaternary ammonium compound that requires transporters to pass through the plasma membrane. Currently, there are three … highest architect salary in the world

Insulin Regulates the Activity of the High-Affinity Choline Transporter ...

WebHemicholinium-3 ( HC3 ), also known as hemicholine, is a drug which blocks the reuptake of choline by the high-affinity choline transporter (ChT; encoded in humans by the gene SLC5A7) at the presynapse. The reuptake of choline is the rate-limiting step in the synthesis of acetylcholine; hence, hemicholinium-3 decreases the synthesis of ... WebA choline uptake system with a high affinity for choline has long been assumed to be present in cholinergic neurons. Very recently, the molecular entity for the high-affinity … WebSLC44A1 is detected in both the plasma and mitochondrial membranes where the protein is able to transport choline at high affinity and in a Na(+)-independent manner. The … highest arches

Choline transporter-like protein 1 - Wikipedia

The high-affinity choline transporter: a critical protein for ...

WebCorpus ID: 40114318; Troxonium-like inhibitors of the high affinity uptake of choline in mouse brain synaptosomes in vitro. @article{Lindborg1984TroxoniumlikeIO, title={Troxonium-like inhibitors of the high affinity uptake of choline in mouse brain synaptosomes in vitro.}, author={Bjoern Gunnar Lindborg and Kristina Crona and … Web1 de jan. de 2024 · The existence of high- and low-affinity transporters is a natural strategy to cope with fluctuations with ethanolamine availability. The high-affinity CTL1 transport … how food express lafayette laWeb1 de out. de 2002 · High-affinity choline transporter 1. Gene. ChT. Status. UniProtKB reviewed (Swiss-Prot) Organism. Drosophila melanogaster ... Function. function. Imports choline from the extracellular space to the neuron with high affinity. Rate-limiting step in acetylcholine synthesis. Sodium ion and chloride ion dependent (By similarity). By ... how food is made in space

"Web1 de mai. de 2003 · High-affinity choline uptake (HACU) was one of the last features of cholinergic signaling to be defined at a molecular level, achieved through the cloning of … " - High affinity choline transporter 1-like

High affinity choline transporter 1-like

Molecular properties of the high-affinity choline transporter CHT1

Web20 de set. de 2024 · Brain microvascular endothelial cells, which comprise part of the blood–brain barrier, take up extracellular choline via intermediate-affinity choline transporter-like protein 1 (CTL1) and low-affinity CTL2 transporters. Web31 de out. de 2000 · Here we report the molecular cloning and functional characterization of the human high-affinity choline transporter (hCHT1). The hCHT1 exhibits significant …

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WebDOI: 10.1016/S0024-3205(03)00088-2 Corpus ID: 12543843; Expression of the high-affinity choline transporter CHT1 in epithelia. @article{Pfeil2003ExpressionOT, title={Expression of the high-affinity choline transporter CHT1 in epithelia.}, author={Uwe Pfeil and Rainer Viktor Haberberger and Katrin Susanne Lips and Lars Eberling and … WebCholine transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters. Adrian Taylor. Adrian Taylor. ... high-affinity (K 1 = 66.5 ± 8.5 μM) and low-affinity (K 2 = 299.0 ± 13.1 μM) Etn bindings were similar to COS-7 cells bindings (K 1 = 55.6 ± 14.8 μM and K 2 = 277.3 ± 7.9 μM).

WebThe high-affinity choline transporter: a critical protein for sustaining cholinergic signaling as revealed in studies of genetically altered mice Authors M H Bazalakova 1 , R D … WebThe high-affinity choline transporter (ChT) also known as solute carrier family 5 member 7 is a protein in humans that is encoded by the SLC5A7 gene. It is a cell membrane …

Web10 de jul. de 2015 · Cuddy LK, Gordon AC, Black SAG, Jaworski E, Ferguson SSG, Rylett RJ. Peroxynitrite donor SIN-1 alters high-affinity choline transporter activity by modifying its intracellular trafficking. J Neurosci. 2012;32:5573–84. pmid:22514319 . View Article PubMed/NCBI Google Scholar 34. Web22 de jul. de 2024 · The first transporter is high-affinity choline transporter 1 (CHT1) that is expressed in cholinergic neurons and is linked to acetylcholine synthesis, which has a high affinity for choline. The second is organic cationic transporters OCT1 and OCT2 that have low affinity for choline, which recognize many cationic substances, and are mainly …

Web1 de out. de 2014 · A single nucleotide polymorphism (SNP) for human CHT1 has been identified, which has a replacement from isoleucine to valine in the third transmembrane segment and shows the choline uptake activity of 50-60% as much as that of wild-typeCHT1. This article summarizes molecular properties of the high-affinity choline …

WebCholinergic neurons are crucial in learning and memory 1, 2, and cholinergic deficits are correlated with the severity of dementia 3. High-affinity choline uptake is the rate … highest aqi recorded in delhiWebThe molecular entity for the high-affinity choline transporter was identified and is designated CHT1, which mediates Na+- and Cl−-dependent choline uptake with high sensitivity to hemicholinium-3 and has been characterized both at the molecular and functional levels. The cholinergic neurons have long been a model for biochemical … how food is cannedWebArchived from the original (PDF) on 2024-03-04. Fullerton MD, Wagner L, Yuan Z, Bakovic M (April 2006). "Impaired trafficking of choline transporter-like protein-1 at plasma … how food is digested in stomach how food impacts mental healthWebLOC799259 high-affinity choline transporter 1-like [ (zebrafish)] Gene ID: 799259, updated on 4-Nov-2024. highest arch support sandalsWebGene ID: 105911781, updated on 2-Sep-2024. Summary Other designations. high affinity choline transporter 1-like how food insecurity affects mental healthWeb1 de mar. de 2001 · High affinity choline transporter 1 Alternative names Hemicholinium-3-sensitive choline transporter ( CHT) Solute carrier family 5 member 7 Gene names … highest area of break ins