WebMETHODS: Bronchoalveolar lavage fluid was obtained from a house dust mite (HDM) induced murine asthma model exposed to DEP. GSH, … WebMay 6, 2024 · Despite of the induction of mucus and Th2 cytokines in OVA-induced acute allergic asthma model, IL-9 slightly affects the cellular changes in asthma . To understand the role of IL-9 in the inflammation process of asthma, the mice in the present study were sensitized by intraperitoneal injection of HDM in aluminum salts to initiate sever lung ...
Vaccination against IL-33 Inhibits Airway Hyperresponsiveness and ...
WebJan 29, 2024 · Recently, fibroblast growth factor 2 (FGF2) has been reported to be an inflammatory regulator; however, its role in asthma remains elusive. This study aimed to investigate the immunomodulatory role of FGF2 in asthma. First, FGF2 expression was characterised in clinical asthma samples and the house dust mite (HDM)-induced … WebFeb 7, 2015 · Here, a murine model for HDM-allergic asthma was used that mimics human features of asthmatic disease such as HDM-induced AHR, airway inflammation and pulmonary cytokine release [11,35,36]. Airway responsiveness upon methacholine exposure in HDM-allergic mice was significantly increased when compared to HDM-PBS control mice. európai unió hivatalos lapja közbeszerzés
Evaluating Immune Responses in a Mouse House Dust Mite (HDM)-induced …
WebMar 13, 2024 · Even in the same HDM-induced asthma mouse model, it is possible to create an acute asthma model, a chronic asthma model, and a remodeling model depending on the amount of antigen exposure and … WebApr 21, 2024 · reuteri protects against airway inflammation in HDM-induced asthma model. In order to prove the impact of different Lactobacillus species on the development of airway inflammation, airway inflammatory cell infiltrate and goblet cell hyperplasia were assessed. For light microscopy and morphometry, mouse lung sections were stained with H&E and ... WebApr 7, 2024 · Activated airway epithelial cells are the major source of CXCL10 in the lungs , which has been shown to be involved in both bronchial inflammation and airway hyper-responsiveness in a mouse model of asthma . CXCL10 is thought to be induced by Th1 cytokine IFN-γ in a variety of cells that promotes Th1-biased airway inflammation . heh ecampus